Product Overview
Demineralized bone chips and particulates designed to promote bone healing in patients with a high risk of non-union
Benefits
• Osteoinductive Potential: Demineralized using proprietary PAD® technology that targets optimal residual calcium levels of 1-4% without compromising the grafts inherent osteoconductive properties or osteoinductive potential1-4
• Osteoconductive: Natural bone matrix facilitates cell attachment and proliferation, and vascular in-growth
• Sterile: Sterilized using proprietary and patented Allowash XG® technology which provides a sterility assurance level of 10-6, without compromising the graft’s inherent osteoconductive properties5
• Versatile: Available in multiple sizes and volumes to meet surgical needs
• Absorbent: Absorbs and retains bioactive fluids like blood, platelet rich plasma (PRP), and bone marrow aspirate (BMA)
Zhang M, Powers R, Wolfinbarger L. (1997). Effect(s) of demineralization process on the osteoinductivity of demineralized bone matrix. J Periodontol, 68:1085-1092.
Turonis JW, McPherson JC 3rd, Cuening MF. (2006). The affects of residual calcium in decalcified freeze-dried bone allograft in a critical-sized defect in the Rattus norvegicus calvarium. J Oral Implantol. 32(2), 55-62.
Herold RW, Pashley DH, Cuening MF. (2002). Effects of varying degrees of allograft decalcification on the cultured porcine osteoclast cells. J Periodontol, 72(2), 213-219.
Mott DA, Mailhot J, Cuenin MF, Sharawy M, Borke J. (2002). Enhancement of osteoblast proliferation in vitro by selective enrichment of demineralized freeze-dried bone allograft with specific growth factors. J Oral Implantiol, 28(2), 57-66.
Eisenlohr LM. “Allograft Tissue Sterilization Using Allowash XG®.” 2007 Bio-Implants Brief.
Clinical Application
• Any surgical application that requires bone void filler
Freeze-Dried Description Size
DCC1/4
Demineralized Cortical/Cancellous
20 cc (https://www.lifenethealth.org/)
