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Collagenase SANTYL Ointment is the only enzymatic debrider approved by the FDA for use in the U.S. It selectively removes necrotic tissue without harming granulation tissue.

Collagenase SANTYL Ointment is indicated for debriding chronic dermal ulcers and severely burned areas.

Occasional slight transient erythema has been noted in surrounding tissue when applied outside the wound. One case of systemic hypersensitivity has been reported after 1 year of treatment with collagenase and cortisone. Use of Collagenase SANTYL Ointment should be terminated when debridement is complete and granulation tissue is well established.
(http://www.smith-nephew.com/)

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